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A third-person perspective on co-speech action gestures in Parkinson ' s disease
Parkinson's disease Gesture Motor imagery Language Action simulation
2016/5/3
A combination of impaired motor and cognitive function in Parkinson's disease (PD) can impact on language and communication, with patients exhibiting a particular difficulty processing action verbs. C...
The UK10K project identifies rare variants in health and disease
health and disease UK10K project identifies
2015/12/21
The contribution of rare and low-frequency variants to human traits is largely unexplored. Here we describe insights
from sequencing whole genomes (low read depth, 73) or exomes (high read depth, 803...
The homozygosity index (HI) approach reveals high allele frequency for Wilson disease in the Sardinian population
Wilson disease genetic epidemiology consanguinity homozygosity index
2015/4/24
Wilson disease (WD) is an autosomal recessive disorder resulting in pathological progressive copper accumulation in liver and other tissues. The worldwide prevalence (P) is about 30/million, while in ...
An event-based model for disease progression and its application in familial Alzheimer's disease and Huntington's disease
Disease progression MRI Alzheimer's disease Huntington's disease
2015/4/20
Understanding the progression of neurological diseases is vital for accurate and early diagnosis and treatment planning. We introduce a new characterization of disease progression, which describes the...
The impairment of emotion recognition in Huntington’s disease extends to positive emotions
Huntington’s disease Emotion Vocalizations
2015/4/10
Patients with Huntington’s Disease (HD) are impaired in the recognition of emotional
signals. However, the nature and extent of the impairment is controversial: it has variously
been argued to dispr...
An investigation of co-speech gesture production during action description in Parkinson’s disease
Co-speech gesture Communication
2015/4/10
Parkinson’s disease (PD) can impact enormously on speech communication. One aspect of
non-verbal behaviour closely tied to speech is co-speech gesture production. In healthy people,
co-speech gestur...
Alzheimer's Disease Narratives and the Myth of Human Being
dementia Alzheimer's disease illness narrative metaphysics bioethics medicine self story hero myth Cartesian ego nature evolution brain mind body nonself
2015/1/8
The ‘loss of self’ trope is a pervasive shorthand for the prototypical process of Alzheimer's disease (AD) in the popular imagination. Turned into an effect of disease, the disappearance of the self a...
Reaching the Socially Isolated Person with Alzheimer’s Disease Through Group Music Therapy - A Case Report
Music Therapy dementia specific unit Alzheimer’s Disease
2008/11/13
The purpose of this report is to present a case on John, an 82 year old man with Alzheimer's disease, who resides in a dementia specific unit of a nursing home. People with dementia who require instit...